Yves Dauvilliers Selected Research

pitolisant

12/2021	European guideline and expert statements on the management of narcolepsy in adults and children.
12/2021	Time to Onset of Response to Pitolisant for the Treatment of Excessive Daytime Sleepiness and Cataplexy in Patients With Narcolepsy: An Analysis of Randomized, Placebo-Controlled Trials.
1/2021	Pitolisant for Residual Excessive Daytime Sleepiness in OSA Patients Adhering to CPAP: A Randomized Trial.
1/2021	European guideline and expert statements on the management of narcolepsy in adults and children.
1/2020	Pitolisant for Daytime Sleepiness in Patients with Obstructive Sleep Apnea Who Refuse Continuous Positive Airway Pressure Treatment. A Randomized Trial.
10/2019	Long-term use of pitolisant to treat patients with narcolepsy: Harmony III Study.
8/2017	Narcolepsy and Other Central Hypersomnias.
1/2017	Safety and efficacy of pitolisant on cataplexy in patients with narcolepsy: a randomised, double-blind, placebo-controlled trial.
11/2013	Pitolisant versus placebo or modafinil in patients with narcolepsy: a double-blind, randomised trial.
4/2008	An inverse agonist of the histamine H(3) receptor improves wakefulness in narcolepsy: studies in orexin-/- mice and patients.

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Yves Dauvilliers Research Topics

Disease

121	Narcolepsy 01/2022 - 01/2003
73	Cataplexy 01/2022 - 02/2002
62	Disorders of Excessive Somnolence (Hypersomnia) 02/2022 - 01/2004
28	Sleepiness 01/2022 - 04/2008
17	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2022 - 12/2004
17	Sleep Wake Disorders 01/2022 - 01/2005
10	Dementia (Dementias) 01/2022 - 01/2004
10	Parkinson Disease (Parkinson's Disease) 01/2021 - 12/2011
10	Restless Legs Syndrome (Restless Legs) 12/2020 - 03/2007
9	Headache (Headaches) 01/2021 - 06/2011
8	Idiopathic Hypersomnia 11/2022 - 03/2006
7	REM Sleep Behavior Disorder 01/2022 - 10/2013
5	Parasomnias (Parasomnia) 11/2022 - 11/2015
5	Sleep Deprivation 01/2022 - 03/2006
5	Synucleinopathies 01/2022 - 01/2017
5	Obstructive Sleep Apnea 01/2022 - 12/2014
5	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 07/2015
5	Hallucinations (Hallucination) 01/2022 - 01/2004
5	Nausea 01/2020 - 09/2016
5	Sleep Paralysis 10/2019 - 05/2010
4	Parkinsonian Disorders (Parkinsonism) 01/2022 - 03/2011
4	Fatigue 12/2021 - 01/2017
4	Human Influenza (Influenza) 10/2017 - 08/2013
4	Kleine-Levin Syndrome (Syndrome, Kleine-Levin) 01/2016 - 12/2006
3	Cognitive Dysfunction 01/2022 - 09/2012
3	Apnea 01/2021 - 08/2009
3	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2020 - 08/2015
3	Nasopharyngitis 01/2020 - 01/2018
3	Sleep Apnea Syndromes (Sleep Apnea) 01/2019 - 08/2009
3	Multiple System Atrophy 01/2018 - 03/2011
3	Hypertension (High Blood Pressure) 01/2017 - 12/2014
3	Genetic Predisposition to Disease (Genetic Predisposition) 11/2013 - 01/2003
2	Somnambulism (Sleepwalking) 01/2022 - 11/2015
2	Inflammation (Inflammations) 01/2022 - 01/2016
2	Brain Diseases (Brain Disorder) 01/2022 - 01/2019
2	Iron Deficiencies 11/2021 - 01/2019
2	Disease Progression 01/2021 - 12/2011
2	Amyloid Plaque 01/2021 - 01/2019
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 02/2011
2	Rare Diseases (Rare Disease) 01/2019 - 08/2017
2	Vomiting 01/2018 - 09/2016
2	Infections 10/2017 - 08/2017
2	Nervous System Diseases (Neurological Disorders) 01/2017 - 01/2015

Drug/Important Bio-Agent (IBA)

71	OrexinsIBA 01/2022 - 01/2003
28	Pharmaceutical PreparationsIBA 11/2022 - 12/2004
28	Sodium Oxybate (gamma Hydroxybutyrate)FDA Link 01/2022 - 12/2004
17	Modafinil (Provigil)FDA Link 12/2021 - 01/2003
16	Biomarkers (Surrogate Marker)IBA 01/2022 - 06/2014
16	HLA-DQB1 antigen (HLA DQB1)IBA 01/2022 - 02/2002
13	Antidepressive Agents (Antidepressants)IBA 01/2022 - 01/2003
10	Histamine (Histamine Dihydrochloride)FDA Link 01/2022 - 04/2008
10	pitolisantIBA 12/2021 - 04/2008
7	N-(4-aminophenethyl)spiroperidol (NAPS)IBA 12/2021 - 09/2004
7	Dopamine (Intropin)FDA LinkGeneric 01/2021 - 03/2007
6	solriamfetolIBA 01/2022 - 01/2019
6	Biological ProductsIBA 01/2022 - 09/2012
6	Hypnotics and Sedatives (Sedatives)IBA 01/2022 - 12/2004
6	Ferritins (Ferritin)IBA 01/2020 - 05/2010
6	HLA Antigens (Human Leukocyte Antigens)IBA 10/2017 - 01/2006
5	VaccinesIBA 01/2022 - 08/2013
4	MagnesiumIBA 01/2022 - 07/2021
4	EnzymesIBA 01/2022 - 10/2010
4	SodiumIBA 01/2022 - 07/2021
4	CalciumIBA 01/2022 - 07/2021
4	PotassiumIBA 01/2022 - 07/2021
4	SolutionsIBA 01/2022 - 01/2016
4	Methylphenidate (Ritalin)FDA LinkGeneric 12/2021 - 01/2013
4	Amphetamine (Amfetamine)FDA LinkGeneric 12/2021 - 01/2013
4	IronIBA 01/2020 - 11/2010
4	Histamine H3 Receptors (Histamine H3 Receptor)IBA 01/2020 - 11/2013
4	tele-methylhistamineIBA 01/2019 - 10/2012
3	AutoantigensIBA 01/2022 - 03/2010
3	Orexin Receptor AntagonistsIBA 01/2022 - 01/2020
3	Amyloid (Amyloid Fibrils)IBA 01/2022 - 01/2019
3	SynucleinsIBA 01/2022 - 11/2014
3	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2020 - 06/2016
3	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2019 - 01/2013
3	Wakefulness-Promoting AgentsIBA 01/2019 - 08/2017
3	Glucose (Dextrose)FDA LinkGeneric 01/2017 - 03/2010
3	CytokinesIBA 11/2016 - 03/2014
3	Intravenous Immunoglobulins (IVIG)FDA Link 07/2006 - 12/2004
2	AntigensIBA 01/2022 - 12/2011
2	Hemagglutinins (Hemagglutinin)IBA 01/2022 - 01/2016
2	Peptides (Polypeptides)IBA 01/2022 - 10/2010
2	Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric 12/2021 - 01/2021
2	Clomipramine (Anafranil)FDA LinkGeneric 12/2021 - 01/2021
2	rotigotine FDA Link 12/2020 - 09/2016
2	daridorexantIBA 01/2020 - 01/2020
2	HepcidinsIBA 01/2020 - 01/2018
2	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 01/2020 - 01/2019
2	Flecainide (Tambocor)FDA LinkGeneric 11/2019 - 01/2016
2	NeuropeptidesIBA 01/2019 - 04/2008
2	Adrenergic Agents (Adrenergic Drugs)IBA 01/2019 - 05/2013
2	MelatoninIBA 01/2018 - 12/2011
2	Vitamin D FDA LinkGeneric 01/2017 - 01/2011
2	Interleukin-2 (IL2)IBA 11/2016 - 03/2014

Therapy/Procedure

13	Therapeutics 01/2021 - 12/2004
3	Continuous Positive Airway Pressure 01/2020 - 08/2009
2	Bed Rest (Bedrest) 01/2021 - 01/2018
2	Drug Therapy (Chemotherapy) 01/2021 - 05/2013